Using Pradaxa - Interactions with Pradaxa
Interactions with Pradaxa
Pradaxa has few significant drug-drug interactions, and is not metabolized by the cytochrome P450 pathway.1
Pradaxa has been shown to interact with P-gp inhibitors:1
- Co–administration with the following strong P-gp inhibitors is contraindicated: systemic ketoconazole, cyclosporine, itraconazole and dronedarone
- Concomitant treatment with tacrolimus is not recommended
- Caution should be exercised with mild to moderate P-gp inhibitors (e.g. amiodarone, posaconazole, quinidine, verapamil and ticagrelor).
For a full list of contraindications, please read the Pradaxa Summary of Product Characteristics.
- Pradaxa Summary of Product Characteristics 2016. Boehringer Ingelheim.